GM2/GD2 synthase rabbit pAb

• Background:

  Beta-1,4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) Homo sapiens GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G (M3) and G (D3) by a beta-1,4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

• Description:

  Beta-1, 4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) Homo sapiens GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G (M3) and G (D3) by a Beta-1, 4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013],

• Synonyms:

  B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

• Gene ID:

  2583

• UniProt:

  Q00973

• Cellular Locus:

  Golgi apparatus membrane ; Single-pass type II membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human B4GALNT1. AA range:281-330

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight:

  60kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  60 kD

• Subcellular Location:

  Golgi apparatus membrane ; Single-pass type II membrane protein .

• Other Product Names:

  B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl) -galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

• Gene ID (Human):

  2583

• SwissProt (Human):

  Q00973