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Fhit rabbit pAb

CAT: 0855-ES2342-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2342-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Description
This gene, a member of the histidine triad gene family, encodes a diadenosine 5', 5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
Product Name Alternative
FHIT; Bis (5'-adenosyl) -triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5'; 5'''-P1, P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein
UniProt
P49789
Swiss Prot
P49789
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human FHIT. AA range:81-130
Target
Fhit
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
16kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
16kD
Fragment
IgG
Subcellular Location
Cytoplasm . Mitochondrion . Nucleus .
Other Product Names
FHIT; Bis (5'-adenosyl) -triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5'; 5'''-P1, P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein
Gene ID (Human)
2272

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