Exo1 rabbit pAb

• Background:

  This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008],

• Synonyms:

  EXO1; EXOI; HEX1; Exonuclease 1; hExo1; Exonuclease I; hExoI

• Gene ID:

  9156

• UniProt:

  Q9UQ84

• Cellular Locus:

  Nucleus. Colocalizes with PCNA to discrete nuclear foci in S-phase.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human EXO1. AA range:61-110

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IF, ELISA

• Validated Applications:

  WB, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  94kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  94 kD

• Subcellular Location:

  Nucleus . Colocalizes with PCNA to discrete nuclear foci in S-phase.

• Other Product Names:

  EXO1; EXOI; HEX1; Exonuclease 1; hExo1; Exonuclease I; hExoI

• Gene ID (Human):

  9156

• SwissProt (Human):

  Q9UQ84