Products for Research Use Only
RegisterLogin

CYP1A1/2 rabbit pAb

CAT: 0855-ES2093-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2093-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
Description
This gene, CYP1A1, encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016],
UniProt
P04798/P05177
Swiss Prot
P04798/P05177
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A1/2. AA range:71-120
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion inner membrane ; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein . Cytoplasm .
Other Product Names
CYP1A1; Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; CYP1A2; Cytochrome P450 1A2; CYPIA2; Cytochrome P (3) 450; Cytochrome P450 4; Cytochrome P450-P3
Gene ID (Human)
1543/1544

Related Products

CatalogName
ES3954-01CYP11B1/2 rabbit pAb
ES2091-01CYP11B1/2 rabbit pAb
ES2094-01CYP1B1 rabbit pAb
ES4948-01CYP17A1 rabbit pAb
ES2092-01CYP19A1 rabbit pAb
ES4947-01CYP11A1 rabbit pAb
ES4921-01CYP1A2 rabbit pAb
ES4953-01CYP21A2 rabbit pAb
ES4952-01CYP21A2 rabbit pAb
ES2095-01CYP26A1 rabbit pAb

Alternative Products

CatalogName
APRab09629-01CYP1A1/2 Rabbit Polyclonal Antibody
A2159-01CYP1A1 Rabbit pAb
A22182CYP1A1 Rabbit mAb
TA346040CYP1A1 Rabbit Polyclonal Antibody
SL1606R-01Rabbit Anti-CYP1A1 antibody
APR24677N-01CYP1A1 Rabbit pAb (APR24677N)
PA85887HU-01Rabbit Anti-Human CYP1A1/2 Polyclonal Antibody
sc-48432CYP1A1 (B-2)
388039CYP1A1/2 discontinued
C12249-01CYP1A1/2 Antibody

Popular Products