CLC-6 rabbit pAb

• Background:

  Chloride voltage-gated channel 6 (CLCN6) Homo sapiens This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012]

• Description:

  Chloride voltage-gated channel 6 (CLCN6) Homo sapiens This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012],

• Synonyms:

  CLCN6; KIAA0046; Chloride transport protein 6; Chloride channel protein 6; ClC-6

• Gene ID:

  1185

• UniProt:

  P51797

• Cellular Locus:

  Late endosome membrane ; Multi-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat, Monkey

• Reactivity:

  Human; Mouse; Rat; Monkey

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CLCN6. AA range:611-660

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  97kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  97 kD

• Subcellular Location:

  Late endosome membrane ; Multi-pass membrane protein .

• Other Product Names:

  CLCN6; KIAA0046; Chloride transport protein 6; Chloride channel protein 6; ClC-6

• Gene ID (Human):

  1185

• SwissProt (Human):

  P51797