Products for Research Use Only

ChemR23 rabbit pAb

CAT: 0855-ES1969-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES1969-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Developmental stage:Expressed during bone development., function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2) ., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.
Description
Developmental stage: Expressed during bone development. function: Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.
UniProt
Q99788
Swiss Prot
Q99788
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Molecular Weight
42kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
42kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Internalizes efficiently in response to RARRES2. .
Other Product Names
CMKLR1; CHEMR23; DEZ; Chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ
Gene ID (Human)
1240

UniProtKB · Q99788

Chemerin-like receptor 1

CML1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99788
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CMKLR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K6Y5, O75748, Q3KP37, Q5U0H0, Q99789
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix