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CD2BP2 rabbit pAb

CAT: 0855-ES1904-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1904-02Size:100 µL
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Background
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]
Description
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],
Product Name Alternative
CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2
UniProt
O95400
Swiss Prot
O95400
Reactivity
Human; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150
Target
CD2BP2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Cytoplasm. Nucleus. Predominantly nuclear.
Other Product Names
CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2
Gene ID (Human)
10421

UniProtKB · O95400

CD2 antigen cytoplasmic tail-binding protein 2

CD2B2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95400
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD2BP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CD2 cytoplasmic domain-binding protein 2, CD2 tail-binding protein 2
EC number
—
Processing
—
Secondary accessions
B2RDX2, Q9ULP2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Cellular component

CytoplasmNucleus

Biological process

mRNA processingmRNA splicing

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