BTF rabbit pAb

• Background :

  This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• UniProt :

  Q9NYF8

• Swiss Prot :

  Q9NYF8

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  106kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  106kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .

• Other Product Names :

  BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf

• Gene ID (Human) :

  9774