AIM2 rabbit pAb

• Background:

  AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]

• Description:

  AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008],

• Synonyms:

  AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2

• Gene ID:

  9447

• UniProt:

  O14862

• Cellular Locus:

  Nucleus. Cytoplasm. Activated inflammasomes can aggregate in the cytosol as speck-like particles.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human AIM2. AA range:51-100

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  39kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  39 kD

• Subcellular Location:

  Nucleus. Cytoplasm. Activated inflammasomes can aggregate in the cytosol as speck-like particles.

• Other Product Names:

  AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2

• Gene ID (Human):

  9447

• SwissProt (Human):

  O14862