AHA-1 rabbit pAb

• Background :

  Function:Cochaperone that stimulates HSP90 ATPase activity (By similarity) . May affect a step in the endoplasmic reticulum to Golgi trafficking., induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG) ., similarity:Belongs to the AHA1 family., subcellular location:May transiently interact with the endoplasmic reticulum., subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G) . Interacts with GCH1., tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

• Description :

  Function: Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking. induction: By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG). similarity: Belongs to the AHA1 family. subcellular location: May transiently interact with the endoplasmic reticulum. subunit: Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1. tissue specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

• UniProt :

  O95433

• Swiss Prot :

  O95433

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300; ELISA 1:5000-20000. Not yet tested in other applications.

• Molecular Weight :

  38kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  38kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.

• Other Product Names :

  AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38

• Gene ID (Human) :

  10598