NBR1 Rabbit pAb

• Background:

  NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

• Description:

  NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

• UniProt:

  Q14596

• Swiss Prot:

  Q14596

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant Protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC

• Concentration:

  1mg/mL

• Dilution:

  IHC 1:100-200

• Molecular Weight:

  120kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  120kDa

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm, Cytoplasmic vesicle, Lysosome

• Other Product Names:

  1A13B, MIG19, Nbr1

• Gene ID (Human):

  4077