ATG5 Rabbit pAb

• Background:

  Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

• Description:

  Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

• Synonyms:

  APG5, APG5L, ASP, Autophage Cysteine protein5 antibody

• Gene ID:

  9494

• UniProt:

  Q9H1Y0

• Cellular Locus:

  Cytoplasm, Membrane

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant Protein

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC

• Validated Applications:

  IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:100-200

• Molecular Weight:

  32kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  32 kDa

• Subcellular Location:

  Cytoplasm, Membrane

• Other Product Names:

  APG5, APG5L, ASP, Autophage Cysteine protein5 antibody

• Gene ID (Human):

  9494

• SwissProt (Human):

  Q9H1Y0