IkB α Rabbit pAb

• Background :

  Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.

• Description :

  Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.

• UniProt :

  P25963

• Swiss Prot :

  P25963

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant Protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB, IHC

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1,000 IHC 1:100-200

• Molecular Weight :

  40kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  40kDa

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, Nucleus

• Other Product Names :

  I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody

• Gene ID (Human) :

  4792