CHOP (2B1) Mouse mAb

• Background:

  CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase.

• Description:

  CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase.

• UniProt:

  P35638

• Swiss Prot:

  P35638

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB, IHC

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1,000-2,000 IHC 1:100-200

• Molecular Weight:

  27kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  27kDa

• Fragment:

  IgG1

• Subcellular Location:

  Nucleus

• Other Product Names:

  GADD153, DDIT3, MGC4154

• Gene ID (Human):

  1649