CHOP (2B1) Mouse mAb

• Background:

  CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase.

• Description:

  CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase.

• Synonyms:

  GADD153, DDIT3, MGC4154

• Gene ID:

  1649

• UniProt:

  P35638

• Cellular Locus:

  Nucleus

• Host:

  Mouse

• Species Reactivity:

  Human, Rat, Mouse

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Source:

  Mouse

• Applications:

  WB, IHC

• Validated Applications:

  WB, IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1,000-2,000 IHC 1:100-200

• Molecular Weight:

  27kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  27 kDa

• Subcellular Location:

  Nucleus

• Other Product Names:

  GADD153, DDIT3, MGC4154

• Gene ID (Human):

  1649

• SwissProt (Human):

  P35638