IDE/Insulin Degrading Enzyme Mouse mAb

IDE/Insulin Degrading Enzyme Mouse mAb

• Description: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
• Synonyms: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
• Gene ID: 3416
• UniProt: P14735
• Cellular Locus: Cell membrane, Cytoplasm, Membrane, Secreted
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Synthetic Peptide
• Clonality: Monoclonal
• Validated Applications: WB, IHC
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:1,000 IHC 1:200
• Molecular Weight: 118kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.