Insulin rabbit pAb

CAT: 0855-ES5905-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES5905-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Description
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
UniProt
P01308
Swiss Prot
P01308
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Insulin. AA range:49-98
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
INS; Insulin
Gene ID (Human)
3630

Related Products

CatalogName
ES5912-01Insulin R rabbit pAb
ES5909-01Insulin R (phospho Tyr1361) rabbit pAb
ES5907-01Insulin R (phospho Thr1375) rabbit pAb
ES15451-01Insulin Receptor β (phospho-Tyr1345) rabbit pAb
ES5908-01Insulin R (phospho Tyr1355) rabbit pAb
ES2627-01Insulin R Rabbit Polyclonal Antibody
ES8798-01Insulin R Rabbit Polyclonal Antibody
ELK10621-01Rabbit INS (Insulin) ELISA Kit
ES5911-01Insulin R Rabbit Polyclonal Antibody
ES5910-01Insulin R Rabbit Polyclonal Antibody

Alternative Products

CatalogName
RC-RB7009Rabbit Insulin
E45R12723N-100Insulin Rabbit mAb
E47R0855Insulin Rabbit pAb
RPU60171-01Prokaryotic Rabbit Insulin

Popular Products