IDE/Insulin Degrading Enzyme Mouse mAb
CAT:
855-EM1083-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IDE/Insulin Degrading Enzyme Mouse mAb
- Description: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
- Synonyms: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
- Gene ID: 3416
- UniProt: P14735
- Cellular Locus: Cell membrane, Cytoplasm, Membrane, Secreted
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Synthetic Peptide
- Clonality: Monoclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1,000 IHC 1:200
- Molecular Weight: 118kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.