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CD23 Mouse mAb

CAT: 0855-EM1082-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-EM1082-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.
Description
CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.
Product Name Alternative
BLAST 2, CD23A, CLEC4J, Fc epsilon RII, FCE2, FCER2, IGEBF, Lymphocyte IgE receptor
UniProt
P06734
Swiss Prot
P06734
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:1,000 IHC 1:200-500
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
36kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
36kDa
Fragment
IgG1
Subcellular Location
Cell membrane, Membrane, Secreted
Other Product Names
BLAST 2, CD23A, CLEC4J, Fc epsilon RII, FCE2, FCER2, IGEBF, Lymphocyte IgE receptor
Gene ID (Human)
2208

UniProtKB · P06734

Low affinity immunoglobulin epsilon Fc receptor

FCER2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06734
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FCER2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumLectinMetal-binding

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinLipoproteinPalmitateProteoglycan

Molecular function

IgE-binding proteinReceptor

Domain

RepeatSignal-anchorTransmembraneTransmembrane helix

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