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CK17 Mouse mAb

CAT: 0855-EM1081-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-EM1081-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytokeratin17 (CK17) is a protein that in humans is encoded by the KRT17 gene. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Description
Cytokeratin17 (CK17) is a protein that in humans is encoded by the KRT17 gene. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Product Name Alternative
39.1, Cytokeratin 17, K17, keratin 17, KRT17, PC, PC2, PCHC1
UniProt
Q04695
Swiss Prot
Q04695
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC, IF
Concentration
1mg/mL
Dilution
WB 1:1,000 IHC 1:200 IP 1:200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
48kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
48kDa
Fragment
IgG1
Subcellular Location
Cytoplasm
Other Product Names
39.1, Cytokeratin 17, K17, keratin 17, KRT17, PC, PC2, PCHC1
Gene ID (Human)
3872

UniProtKB · Q04695

Keratin, type I cytoskeletal 17

K1C17_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q04695
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KRT17
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5Z1M9, A5Z1N0, A5Z1N1, A5Z1N2, A6NDV6, A6NKQ2, Q6IP98, Q8N1P6
Protein keywords

Domain

Coiled coil

Cellular component

CytoplasmIntermediate filamentKeratin

Disease

Disease variantEctodermal dysplasiaPalmoplantar keratoderma

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Technical term

Proteomics identificationReference proteome