Ethyl (E)-ferulate
CAT:
804-HY-W590845
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Ethyl (E)-ferulate
- CAS Number: 28028-62-8
- UNSPSC Description: Ethyl (E)-ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056)-induced acute lung injury. Additionally, Ethyl (E)-ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E)-ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].
- Target Antigen: AMPK; Keap1-Nrf2
- Type: Reference compound
- Related Pathways: Epigenetics;NF-κB;PI3K/Akt/mTOR
- Field of Research: Inflammation/Immunology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/ethyl-e-ferulate.html
- Smiles: CCOC(/C=C/C1=CC(OC)=C(C=C1)O)=O
- Molecular Weight: 222.24
- References & Citations: [1]Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42(12):2069-2081.|[2]Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19(6): 8124-8139.|[3]Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29(2):73-83.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported