Ethyl (E)-ferulate

• UNSPSC Description:

  Ethyl (E)-ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056)-induced acute lung injury. Additionally, Ethyl (E)-ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E)-ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].

• Target Antigen:

  AMPK; Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;NF-κB;PI3K/Akt/mTOR

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ethyl-e-ferulate.html

• Smiles:

  CCOC(/C=C/C1=CC(OC)=C(C=C1)O)=O

• Molecular Weight:

  222.24

• References & Citations:

  [1]Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42(12):2069-2081.|[2]Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19(6): 8124-8139.|[3]Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29(2):73-83.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  28028-62-8