Ethyl (E) -ferulate

• Description :

  Ethyl (E) -ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056) -induced acute lung injury. Additionally, Ethyl (E) -ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E) -ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  AMPK; Keap1-Nrf2

• Type :

  Reference compound

• Related Pathways :

  Epigenetics; NF-κB; PI3K/Akt/mTOR

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ethyl-e-ferulate.html

• Smiles :

  CCOC(/C=C/C1=CC(OC)=C(C=C1)O)=O

• Molecular Formula :

  C12H14O4

• Molecular Weight :

  222.24

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42 (12) :2069-2081.|[2]Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19 (6) : 8124-8139.|[3]Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29 (2) :73-83.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [28028-62-8]