Ethyl (E) -ferulate

CAT: 0804-HY-W590845Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W590845Size:1 Each
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Description
Ethyl (E) -ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056) -induced acute lung injury. Additionally, Ethyl (E) -ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E) -ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].
CAS Number
[28028-62-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
AMPK; Keap1-Nrf2
Type
Reference compound
Related Pathways
Epigenetics; NF-κB; PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ethyl-e-ferulate.html
Smiles
CCOC(/C=C/C1=CC(OC)=C(C=C1)O)=O
Molecular Formula
C12H14O4
Molecular Weight
222.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42 (12) :2069-2081.|[2]Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19 (6) : 8124-8139.|[3]Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29 (2) :73-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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