PF-04449913

CAT: 0026-B2467-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2467-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-04449913 is a potent and orally bioavailable smoothened (SMO) inhibitor. PF-04449913 binds to human SMO with an IC₅₀ of 4 nM. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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