GSDMD antibody
CAT:
710-FNab10648
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GSDMD antibody
- Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
- Synonyms: Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD)|Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD)|Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1
- CAS Number: 9007-83-4
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Immunogen: gasdermin D
- Target: GSDMD
- Clonality: Monoclonal
- Isotype: IgG2a
- Applications: ELISA, WB, IF
- Purification: Protein A+G purification
- Dilution: WB: 1:1000-1:5000; IF: 1:20-1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)