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Xylocydine

CAT: 0804-HY-118310Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118310Size:1 Each
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Description
Xylocydine is an inhibitor of CDK1/2, inhibiting CDK function in various apoptotic processes. Xylocydine specifically blocks CDK1 and CDK2 activity with IC50 of 1.4 nM and 61 nM, respectively. In addition, Xylocydine downregulates phosphorylated nucleolin and retinoblastoma protein levels.[1].
CAS Number
685901-63-7
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/xylocydine.html
Smiles
O=C(N)C1=C(N([C@H]2O[C@@H](CO)[C@@H](O)[C@@H]2O)C3=NC=NC(N)=C31)Br
Molecular Formula
C12H14BrN5O5
Molecular Weight
388.17
References & Citations
[1]Xylocydine, a Novel Inhibitor of Cyclin-Dependent Kinases, Prevents the Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Apoptotic Cell Death of SK-HEP-1 Cells
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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