Defactinib

• Description:

  FAK phosphorylation inhibitor

• Product Name Alternative:

  N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide

• Field of Research:

  Tyrosine Kinase FAK

• Purity:

  0.9867

• Solubility:

  insoluble in EtOH; insoluble in H2O; ≥160.2 mg/mL in DMSO

• Smiles:

  CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F

• Molecular Formula:

  C20H21F3N8O3S

• Molecular Weight:

  510.49

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1073154-85-4