Me-(S,R,S)-AHPC-PEG2-OTs

Me-(S,R,S)-AHPC-PEG2-OTs

• CAS Number: 3033933-58-0
• UNSPSC Description: Me-(S,R,S)-AHPC-PEG2-OTs is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates) used in the synthesis of PROTAC HIF-1α degrader-1 (HY-168641)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/me-s-r-s-ahpc-peg2-ots.html
• Smiles: O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NCCOCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O
• Molecular Weight: 730.93
• References & Citations: [1]Li Y, et al. Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC). Bioorg Chem. 2024 Nov 4;153:107943.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported