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VAPA rabbit pAb

CAT: 0855-ES12389-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12389-01Size:50 µL
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Background
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
UniProt
Q9P0L0
Swiss Prot
Q9P0L0
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human VAPA AA range: 34-84
Target
VAPA
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Cell membrane ; Single-pass type IV membrane protein . Cell junction, tight junction . Nucleus membrane . Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells. .
Gene ID (Human)
9218

UniProtKB · Q9P0L0

Vesicle-associated membrane protein-associated protein A

VAPA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9P0L0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VAPA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VAMP-A, VAMP-associated protein A, VAP-A
EC number
—
Processing
—
Secondary accessions
A6NDZ0, D3DUI3, O75453, Q5U0E7, Q9UBZ2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bondPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneEndoplasmic reticulumMembraneNucleusTight junction

Domain

Coiled coilTransmembraneTransmembrane helix

Biological process

Host-virus interaction

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