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Licochalcone E

CAT: 0804-HY-N4182-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N4182-01Size:1 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1].
CAS Number
[864232-34-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; Autophagy; p38 MAPK
Type
Natural Products
Related Pathways
Autophagy; MAPK/ERK Pathway; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/licochalcone-e.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(O)C=C1)/C=C/C2=CC([C@@H](C)C(C)=C)=C(O)C=C2OC
Molecular Formula
C21H22O4
Molecular Weight
338.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14 (6) :10926-43.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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