RegisterLogin

Licochalcone D

CAT: 0804-HY-N4187-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N4187-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza uralensis, is a potent and orally active inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2].
CAS Number
[144506-15-0]
UNSPSC
12352005
Target
Apoptosis; NF-κB; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/licochalcone-d.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(O)C(C/C=C(C)\C)=C1)/C=C/C2=CC=C(O)C(O)=C2OC
Molecular Formula
C21H22O5
Molecular Weight
354.40
References & Citations
[1]Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9 (4) :499-507.|[2]Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39 (5) :2160-2170.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
RelA/p65

Related Products

CatalogName
HY-N0372-01Licochalcone A
HY-N0372R-01Licochalcone A (Standard)
HY-N0373-01Licochalcone B
HY-N4182-01Licochalcone E
HY-N0374-01Licochalcone C
HY-N0373RLicochalcone B (Standard)
HY-N0379S11-01D-Mannose-d
HY-N9914S-01D-Psicose-d
HY-W018772S6-01D-Ribose-d
HY-N7092S8-01D-Fructose-d

Alternative Products

CatalogName
MBS3605162-01Licochalcone A
TBZ0551Licochalcone
MBS578467LICOCHALCONE-A
AB0547Licochalcone B
371642Licochalcone A discontinued
T4518-01Licochalcone D
TN1055-01Licochalcone E
TB0560Licochalcone C
ALX-430-124-M005Licochalcone A (synthetic)

Popular Products