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YTHDC2 antibody

CAT: 0710-FNab10487Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab10487Size:100 µg
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Background
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
Synonyms
3'-5' RNA helicase YTHDC2|YTH domain-containing protein 2 (hYTHDC2) |YTHDC2
Gene ID
64848
UniProt
Q9H6S0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
3'-5' RNA helicase YTHDC2
Target
YTHDC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
160 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
Immunogen Sequence
1131-1430aa

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