PLEK2 rabbit pAb

• Background:

  The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]

• Description:

  The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015],

• UniProt:

  Q9NYT0

• Swiss Prot:

  Q9NYT0

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human PLEK2 AA range: 5-55

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000

• Molecular Weight:

  38kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  38kD

• Fragment:

  IgG

• Subcellular Location:

  Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.

• Other Product Names:

  Pleckstrin-2

• Gene ID (Human):

  26499