Recombinant Human CXCL10

Recombinant Human CXCL10

• Description: Recombinant human CXCL10
• Product Name Alternative: rHuCXCL10, IP-10
• CAS Number: 9000-83-3
• UniProt: P02778
• Reactivity: Human
• Target Antigen: C-X-C motif chemokine 10
• Target: CXCL10
• Type: Protein
• Applications: Migration assay
• Concentration: Lot Specific
• Dilution: Centrifuge tube prior to resuspending. Recommended at 100ug/ml in sterile distilled water.
• Additionnal Information: Endotoxin Level: <0.01 EU per 1ug of protein by LAL method.Migration Assay in cells expressing recombinant CXCR3.
• Storage Conditions: 12 months from date of receipt, -20°C to -70°C, as supplied. 1 month,- 20°C to -70°C, under sterile conditions after reconstitution. Best if used immediately after reconstitution. Avoid multiple freeze-thaw cycles.
• Specificity: CXCL10
• Target Background: CXCL10, also known as γ-interferon-inducible protein (IP-10), was originally identified as an IFN-gamma-inducible gene in endothelial cells, fibroblasts, and monocytes. IP-10 signals through the CXCR3 receptor to attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, suggesting that IP-10 might be a key mediator of the IFN-gamma response.