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CPSF5 rabbit pAb

CAT: 0855-ES17253-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES17253-01Size:50 µL
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Background
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008],
UniProt
O43809
Swiss Prot
O43809
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human CPSF5 AA range: 25-75
Target
CPSF5
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm in a transcription- and XPO1/CRM1-independent manner, most probably in complex with the cleavage factor Im complex (CFIm) (PubMed:19864460) . In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles (PubMed:15169763) . .
Gene ID (Human)
11051

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