ABBV-167
CAT:
804-HY-142209-05
Size:
100 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ABBV-167
- CAS Number: 1351456-78-4
- UNSPSC Description: ABBV-167 is a phosphate proagent of the BCL-2 inhibitor venetoclax.
- Target Antigen: Bcl-2 Family
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/abbv-167.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC1(CCC(CN2CCN(CC2)C3=CC(OC4=CN(C5=NC=CC5=C4)COP(O)(O)=O)=C(C=C3)C(NS(=O)(C6=CC([N+]([O-])=O)=C(C=C6)NCC7CCOCC7)=O)=O)=C(C1)C8=CC=C(C=C8)Cl)C
- Molecular Weight: 978.45
- References & Citations: [1]Salem AH, et al. Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers. Mol Cancer Ther. 2021 Jun;20(6):999-1008.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported