RIPK-IN-4

• Description:

  RIPK-IN-4 is a selective RIPK2 inhibitor with an IC50 value of 3 nM. RIPK-IN-4 can be used for the research of inflammatory diseases[1].

• UNSPSC:

  12352005

• Target:

  RIP kinase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ripk-in-4.html

• Concentration:

  10mM

• Purity:

  99.57

• Solubility:

  DMSO : 31.25 mg/mL (ultrasonic)

• Smiles:

  O=S(C1=CN2C(C3=CC(N)=NC(F)=C3)=CN=C2C=C1OCC)(C(C)(C)C)=O

• Molecular Formula:

  C18H21FN4O3S

• Molecular Weight:

  392.45

• References & Citations:

  [1]He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8 (10) :1048-1053.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  RIPK2

• CAS Number:

  2141969-56-2