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Atovaquone (Standard)

CAT: 0804-HY-13832R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13832R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia[1][2].
CAS Number
95233-18-4
Product Name Alternative
Atavaquone (Standard)
UNSPSC
12352005
Target
Antibiotic; Bacterial; Cytochrome P450; Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/atovaquone-standard.html
Smiles
O=C1C([C@H]2CC[C@H](C3=CC=C(Cl)C=C3)CC2)=C(O)C(C4=C1C=CC=C4)=O
Molecular Formula
C22H19ClO3
Molecular Weight
366.84
References & Citations
[1]Nilsen A, et al. Quinolone-3-diarylethers: a new class of antimalarial drug.Sci Transl Med. 2013 Mar 20;5 (177) :177ra37.|[2]Schöler N, et al. Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosis.Antimicrob Agents Chemother. 2001 Jun;45 (6) :1771-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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