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Voxvoganan (trihydrochloride)

CAT:
804-HY-119123A-03
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Voxvoganan (trihydrochloride) - image 1

Voxvoganan (trihydrochloride)

  • UNSPSC Description: Voxvoganan (LTX-109) trihydrochloride, a topical antimicrobial, is highly effective against S. aureus with a MIC range of 2 to 4 μg/mL. Voxvoganan trihydrochloride can be used for the research of bacterial skin infections, fungal infections and nasal decolonisation of MRSA[1][2].
  • Target Antigen: Bacterial; Fungal
  • Type: Reference compound
  • Related Pathways: Anti-infection
  • Field of Research: Infection
  • Assay Protocol: https://www.medchemexpress.com/voxvoganan-trihydrochloride.html
  • Purity: 98.13
  • Solubility: DMSO : 140 mg/mL (ultrasonic)
  • Smiles: O=C([C@H](CCCNC(N)=N)N)N[C@H](C(N[C@H](C(NCCC1=CC=CC=C1)=O)CCCNC(N)=N)=O)CC2=C(NC3=C2C=C(C=C3C(C)(C)C)C(C)(C)C)C(C)(C)C.[H]Cl.[H]Cl.[H]Cl
  • Molecular Weight: 897.46
  • References & Citations: [1]Johan Isaksson, et al. A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption. J Med Chem. 2011 Aug 25;54(16):5786-95.|[2]Louis D Saravolatz, et al. In vitro activities of LTX-109, a synthetic antimicrobial peptide, against methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, daptomycin-nonsusceptible, and linezolid-nonsusceptible Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Aug;56(8):4478-82.|[3]L D Saravolatz, et al. Postantibiotic effect and postantibiotic sub-MIC effect of LTX-109 and mupirocin on Staphylococcus aureus blood isolates. Lett Appl Microbiol. 2017 Nov;65(5):410-413.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, stored under nitrogen)
  • Clinical Information: Phase 2