Thalidomide-5-NH-PEG4-NH4 (hydrochloride)

Thalidomide-5-NH-PEG4-NH4 (hydrochloride)

• UNSPSC Description: Thalidomide-5-NH-PEG4-NH4 (hydrochloride) is a synthesized compound that incorporates the Thalidomide (HY-14658)[1].
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-5-nh-peg4-nh4-hydrochloride.html
• Purity: 96.64
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(C(CC1)N2C(C3=CC=C(NCCOCCOCCOCCOCCN)C=C3C2=O)=O)=O.Cl
• Molecular Weight: 528.98
• References & Citations: [1]Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.  [Content Brief]
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported