Glucosylceramide (gaucher's spleen)

Glucosylceramide (gaucher's spleen)

• CAS Number: 85305-87-9
• UNSPSC Description: Glucosylceramides are sphingolipid molecules found in both neuronal and non-neuronal mammalian tissues, as well as in low quantities across various plant species. Elevated levels of glucosylceramides provide cellular protection and prepare certain cells for proliferation; however, they have also been linked to obesity-induced insulin resistance in mice and to neuronal deficits observed in neuronopathic Gaucher disease[1].
• Target Antigen: Endogenous Metabolite
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/glucosylceramide-gaucher-s-spleen.html
• Smiles: O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O)OC[C@H](NC([R])=O)[C@@H](/C=C/CCCCCCCCCCCCC)O)CO)O
• References & Citations: [1]Holland WL, et al. Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev. 2008 Jun;29(4):381-402.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported