Fosfomycin (sodium)

• UNSPSC Description:

  Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1][2].

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fosfomycin-sodium.html

• Purity:

  98.0

• Solubility:

  H2O : 125 mg/mL (ultrasonic)

• Smiles:

  C[C@@H]1O[C@@H]1P(O[Na])(O[Na])=O

• Molecular Weight:

  182.023

• References & Citations:

  [1]Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47.|[2]Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31. 6(4):24. |[3]Inouye S, et al. Protective effect of fosfomycin on the experimental nephrotoxicity induced by dibekacin. J Pharmacobiodyn. 1982 Sep. 5(9):659-69.|[4]Inouye S, et al. Mode of protective action of fosfomycin against dibekacin-induced nephrotoxicity in the dehydrated rats. J Pharmacobiodyn. 1982 Dec. 5(12):941-50.ACS Infect Dis. 2024 Jul 27.|Antibiotics (Basel). 2021 Sep 14;10(9):1110.|bioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13(1):1116.|Front Cell Infect Microbiol. 2019 Jul 15;9:253.|J Med Microbiol. 2019 Mar;68(3):493-502.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  26016-99-9