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Imidapril

CAT: 0804-HY-B1451A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1451A-01Size:5 mg
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Description
Imidapril (TA-6366 free base) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research[1][2].
CAS Number
89371-37-9
Product Name Alternative
TA-6366 (free base)
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE) ; MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/imidapril.html
Purity
99.0
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N(C1=O)[C@@H](CN1C)C(O)=O)[C@H](C)N[C@H](C(OCC)=O)CCC2=CC=CC=C2
Molecular Formula
C20H27N3O6
Molecular Weight
405.44
References & Citations
[1]Robinson DM, et al. Imidapril: a review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure. Drugs. 2007;67 (9) :1359-78.|[2]Yamamoto D, et al. Molecular mechanism of imidapril for cardiovascular protection via inhibition of MMP-9. J Mol Cell Cardiol. 2007 Dec;43 (6) :670-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MMP-9

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