Products for Research Use Only
RegisterLogin

Imidaprilat-d3

CAT: 0804-HY-W739949-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W739949-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Imidaprilat-d3 (6366A-d3) is deuterium labeled Imidaprilate. Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease[1].
CAS Number
1356019-69-6
Product Name Alternative
6366A-d3
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE) ; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
C[C@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)C(N2[C@H](CN(C2=O)C([2H])([2H])[2H])C(O)=O)=O
Molecular Formula
C18H20D3N3O6
Molecular Weight
380.41
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Kubo M, et al. Pharmacological studies on (4S) -1-methyl-3-[ (2S) -2-[N- ((1S) -1-ethoxycarbonyl-3-phenylpropyl) amino] propionyl]-2-oxo-imidazolidine-4-carboxylic acid hydrochloride (TA-6366), a new ACE inhibitor: I. ACE inhibitory and anti-hypertensive activities. Jpn J Pharmacol. 1990 Jun;53 (2) :201-10.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B1451S-01Imidapril-d3 (hydrochloride)
HY-15398S3-01Vitamin D3-d3
HY-132348S1Granisetron-d3 (1-methyl-d3)
HY-150954SL-Methionine-d3 (S-methyl-d3) Methyl-d3-sulfonium Chloride
HY-W758392(±) -Ipratropium-d3 Bromide (N-methyl-d3)
HY-B1213AS-01Trimipramine-d3 (N-methyl-d3) (maleate)
HY-17373S2Posaconazole-d3
HY-15345ASTetrahydrouridine-d3
HY-14771SImeglimin-d3
HY-14283S1-01Luliconazole-d3

Alternative Products

CatalogName
TRC-I275052-1MGImidaprilat-d3
TRC-I275050-10MGImidaprilat
AR-I01373-01Imidaprilat-d5
sc-280821Imidaprilat Benzyl Ester, (Carbonylimidazolidine) tert-butyl Ester-d3
MBS6068343-01Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester-d3
014755Imidaprilat Benzyl Ester, (Carbonylimidazolidine) tert-butyl Ester
MBS6027382-01Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester
I0785-02Imidaprilat-d3 ((4S) -3-{ (2S) -2-[N- ((1S) -1-Carboxy-3-phenyl-d3-propyl) amino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic Acid, Imidapril Diacid-d5)
MBS6080700-01Imidaprilat-d3 ((4S)-3-{(2S)-2-[N-((1S)-1-Carboxy-3-phenyl-d3-propyl)amino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic Acid, Imidapril Diacid-d5)
A5050-01Azithromycin-d3 (CP-62993-d3, XZ-450-d3, Azitrocin-d3, Ribotrex-d3, Sumamed-d3, Trozocina-d3, Zithromaz-d3, Zitromax-d3)

Popular Products