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MrgprX2 antagonist-2

CAT: 0804-HY-145192-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145192-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MrgprX2 antagonist-2 is an MrgprX2 antagonist extracted from patent WO2021092262A1, example E163. MrgprX2 antagonist-2 can be used for the research of inflammatory disorders of the skin[1].
CAS Number
2642346-30-1
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrgprx2-antagonist-2.html
Concentration
10mM
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(F)[C@H](O)CN(CC)C(NC1=CC(OC2=CC(F)=CC(F)=C2)=CC=N1)=O
Molecular Formula
C17H16F5N3O3
Molecular Weight
405.32
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]CEVIKBAS F, et, al. Mrgprx2 antagonists and uses thereof. WO2021092262A1.|[2]Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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