Products for Research Use Only

MrgprX2 antagonist-9

CAT: 0804-HY-178793Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-178793Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MrgprX2 antagonist-9 (compound 10) is a potent Mas-related G protein-coupled receptor X2 (MrgprX2) antagonist with an IC50 value of 0.1-100 nM. MrgprX2 antagonist-9 has the potential for the research of inflammatory[1].
CAS Number
3095296-92-4
UNSPSC
12352005
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O=C(N1CC(C(C)(CNC2=CC(C(F)(F)F)=NC3=CC(C(F)(F)F)=NN32)C4=CC=CC=C4)C1)N
Molecular Formula
C21H20F6N6O
Molecular Weight
486.41
References & Citations
[1]Sabnis RW. Novel Bicyclic Heterocycles as MRGPRX2 Antagonists for Treating Inflammatory Diseases. ACS Med Chem Lett. 2025 Jun 2;16 (6) :980-981.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported