Ceftolozane (TFA)

• Description :

  Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer[1].

• CAS Number :

  [1628046-32-1]

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ceftolozane-tfa.html

• Purity :

  98.17

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  [O-]C(C(F)(F)F)=O.OC(C1=C(C[N+]2=CC(NC(NCCN)=O)=C(N2C)N)CS[C@@]([C@@H]3NC(/C(C4=NSC(N)=N4)=N\OC(C)(C)C(O)=O)=O)([H])N1C3=O)=O

• Molecular Formula :

  C25H31F3N12O10S2

• Molecular Weight :

  780.71

• References & Citations :

  [1]Zhiping Shi, et al. Method for preparing novel crystal form of ceftolozane sulfate. CN117327097. 2024-01-02

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2