Ceftolozane

CAT: 0804-HY-19806Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19806Size:1 Each
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Description
Ceftolozane (CXA-101 free base; FR264205 free base) is a cephalosporin antibiotic with potent activity againstPseudomonas aeruginosa and strains Enterobacteriaceae, with MICs of 0.5 and 0.25-0.5 mg/L[1].
CAS Number
[689293-68-3]
Product Name Alternative
CXA-101 (free base) ; FR264205 (free base)
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ceftolozane.html
Purity
98.78
Solubility
DMSO : 24 mg/mL (ultrasonic; adjust pH to 2 with HCl)
Smiles
CN1[N+](CC(CS[C@]2([H])[C@@H]3NC(/C(C4=NSC(N)=N4)=N\OC(C)(C(O)=O)C)=O)=C(C([O-])=O)N2C3=O)=CC(NC(NCCN)=O)=C1N
Molecular Formula
C23H30N12O8S2
Molecular Weight
666.69
Precautions
H302, H312, H332
References & Citations
[1]Craig WA, et al., In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic mice. Antimicrob Agents Chemother. 2013 Apr;57 (4) :1577-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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