ABD-295

• Description:

  ABD-295, a biphenylsulfide derivative, is an antiresorptive agent, osteoclast inhibitor. ABD-295 has potent inhibitory effects on osteoclastic bone resorption in vitro. ABD-295 prevents ovariectomy-induced bone loss in vivo[1].

• UNSPSC:

  12352005

• Target:

  C-Fms; Nuclear Factor of activated T Cells (NFAT)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Protein Tyrosine Kinase/RTK

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/abd-295.html

• Smiles:

  O=S(C1=CC=C(C2=CC=C(F)C=C2F)C(C)=C1)(NCCCCO)=O

• Molecular Formula:

  C17H19F2NO3S

• Molecular Weight:

  355.40

• References & Citations:

  [1]Iain R Greig, et al. Development and characterization of biphenylsulfonamides as novel inhibitors of bone resorption. J Med Chem. 2006 Dec 14;49 (25) :7487-92.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  871113-99-4