ABD-1970

• Description:

  ABD-1970 is a selective monoacylglycerol lipase (MAGL) inhibitor with IC50s of 15 nM and 29 nM for human and mouse MAGL, respectively. ABD-1970 shows selectivity for MGLL over other members of the serine hydrolase class. ABD-1970 has the potential for the study of neurological disorders[1].

• UNSPSC:

  12352005

• Target:

  MAGL

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Neurological Disease

• Smiles:

  O=C(N1CCN(CC2=CC=C(Cl)C=C2N3CC(O4)CCC4C3)CC1)OC(C(F)(F)F)C(F)(F)F

• Molecular Formula:

  C21H24ClF6N3O3

• Molecular Weight:

  515.88

• References & Citations:

  [1]Cisar JS, et al. Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders. J Med Chem. 2018 Oct 25;61 (20) :9062-9084.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2010154-82-0