Metixene (hydrochloride hydrate)

Metixene (hydrochloride hydrate)

• CAS Number: 7081-40-5
• UNSPSC Description: Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hydrate potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC50 and Ki values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used for the research of parkinsonian[1][2][3].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/Metixene_hydrochloride_hydrate.html
• Purity: 99.92
• Solubility: DMSO : 77.5 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
• Smiles: CN1CC(CCC1)CC2C3=C(C=CC=C3)SC4=C2C=CC=C4.Cl.O
• Molecular Weight: 363.94
• References & Citations: [1]J. Hagenah, et al. Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: further clinical evidence. , 106(3-4), 301–307. doi:10.1007/s007020050159 |[2]S L Levin, et al. Dualism in the effect of cholinolytics upon the human parotid gland deprived of parasympathetic control. Int J Clin Pharmacol Res. 1986;6(5):429-39.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Launched