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8α-Hydroxyhirsutinolide

CAT: 0804-HY-N9699-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N9699-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC50: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea[1].
CAS Number
1394156-45-6
UNSPSC
12352005
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/8α-hydroxyhirsutinolide.html
Solubility
10 mM in DMSO
Smiles
OCC1=C2/C(OC1=O)=C\[C@@]3(O[C@]([C@@H](C[C@@H]2O)C)(CC3)O)C
Molecular Formula
C15H20O6
Molecular Weight
296.32
References & Citations
[1]Youn UJ, et al. Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorg Med Chem Lett. 2012 Sep 1;22 (17) :5559-62.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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