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Voxelotor-d7

CAT: 0804-HY-W728761Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W728761Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Voxelotor-d7 is the deuterium labeled Voxelotor. Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization[1].
Product Name Alternative
GBT 440-d7
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])(C(N1N=CC=C1C2=NC=CC=C2COC3=C(C(O)=CC=C3)C=O)(C([2H])([2H])[2H])[2H])[2H]
Molecular Formula
C19H12D7N3O3
Molecular Weight
344.42
References & Citations
[1]Oksenberg D, et al. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. Br J Haematol. 2016 Oct;175 (1) :141-53.|[2]Oksenberg D, et al. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. Br J Haematol. 2016 Oct;175 (1) :141-53.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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